MCQs in Oral Pathology

Chapter 1: Vesiculobullous diseases

 

1- Which of the following statements is true regarding herpes infections of the trigeminal area:

  1. Reactivation of the herpes simplex virus usually causes cold sores on the lips
  2. Herpetic whitlows can be caught only from patients with primary herpes infections
  3. Post-herpetic neuralgia follows a herpes simplex infection
  4. Post-herpetic neuralgia usually responds well to treatment with carbamazepine
  5. Post-herpetic neuralgia usually occurs in young patients

 

 

 

 

 

The answer is: A

 

2-The lesions found in the buccal mucosa, known as Koplik's spots, are first signs of which of the following

  1. Erythema multiforme
  2. Herpangina
  3. Rubeola
  4. Varicella
  5. Acute lupus erythematosus

 

 

 

 

 

 

The answer is: C

 

 

3-The most important effect of prednisone is regards to treatment of  pemphigus vulgaris and mucous membrane pemphigoid is:

  1. Gluconeogenesis
  2. Potentiation of vasopressors
  3. Suppression of pituitary-adrenal axis
  4. Sodium resorption
  5. Immunosuppression

 

 

 

 

 

The answer is: E

 

4-Which of the following is true about epidermolysis bullosa:

  1. May result in a constricted oral orifice because of scarring
  2. Is a bullous skin disease which may have oral manifestations
  3. May be inherited
  4. May be acquired
  5. All of the above

 

 

 

 

 

The answer is: E

 

5-All of the following would be considered iatrogenic injuries EXCEPT:

  1. Amalgam tattoo
  2. Saliva ejector injury
  3. Chemical burn following medication of cavity preparation
  4. Ulceration resulting from traumatic dental impression
  5. Zoster precipitated by lymphoma

 

 

 

 

 

The answer is: E

 

6-Symptoms of pain and burning sensation at the site where a lesion is about to occur is a feature of which of the following conditions:

  1. Primary syphilis
  2. Mucous membrane pemphigoid
  3. Secondary herpes labialis
  4. Chronic lupus erythematosus
  5. None of the above

 

 

 

 

 

The answer is: C

 

7-Which of the following conditions is not caused by snuff dipping:

  1. Increased incidence of herpes simplex labialis
  2. Mucosal opacification
  3. Gingivitis
  4. Dependence
  5. Tooth abrasion

 

 

 

 

 

The answer is: A

 

8-Eye lesions that may develop into blindness are features of which of the following conditions:

  1. Pemphigus vulgaris
  2. Mucous membrane pemphigoid
  3. Lichen planus
  4. Erythema multiforme
  5. None of the above

 

 

 

 

 

The answer is: B

 

9-Herpes simplex infections are treated with:

  1. Lysine
  2. Topical clobetasol
  3. Acyclovir
  4. Topically applied tetracycline
  5. Prednisone

 

 

 

 

 

The answer is: C

 

10-Diagnosis of mucous membrane pemphigoid can be made by which of the following

  1. Direct immunofluorescence
  2. Fite stain of tissue section
  3. Determination of serum antinuclear antibodies (ANA)
  4. Observed response to trial dose of acyclovir
  5. None of the above

 

 

 

 

 

The answer is: A

 

11-Corticosteroids are contraindicated in the treatment of which of the following conditions

  1. Chronic traumatic ulcers
  2. Pemphigus vulgaris
  3. Herpetiform aphthous ulcers
  4. Hand, foot, and mouth disease
  5. Mucous membrane pemphigoid

 

 

 

 

 

The answer is: D

 

12-Which of the following conditions can be diagnosed using cytologic examination:

  1. Herpes simplex
  2. Recurrent aphthae
  3. Mucous membrane pemphigoid
  4. Erosive lichen planus
  5. Frictional hyperkeratosis

 

 

 

 

 

The answer is: A

 

13-The Tzanck cells in pemphigus vulgaris result from:

  1. Acantholysis
  2. Acanthosis
  3. Intercellular edema
  4. Intracellular edema
  5. Mucous extravasation

 

 

 

 

 

The answer is: A

 

14-Site specificity is a characteristic clinical feature of which of the following conditions when occurring intraorally:

  1. Syphilis
  2. Candidiasis
  3. Histoplasmosis
  4. Intraoral tuberculosis
  5. Secondary herpes simplex infection

 

 

 

 

 

The answer is: E

 

15-The palate and maxillary ridge of a 56-year-old woman contain multiple flat ulcers of 8 weeks duration. She has a positive Nikolsky sign and has no evidence of either skin or lip lesions. Which of the following should receive serious consideration in the clinical differential diagnosis:

  1. Pemphigus vulgaris
  2. Herpangina
  3. Lichen planus
  4. Aphthous stomatitis
  5. Herpes simplex infection

 

 

 

 

 

The answer is: A

 

16-A young adult female patient comes to your clinic complaining of mildly painful ulcers in her hard palate. The ulcers are multiple and confluent. A similar condition has been noted in the patient on two previous occasions. This is most likely:

  1. Trauma
  2. Herpangina
  3. Candidiasis
  4. Riga-Fede disease
  5. Secondary herpes

 

 

 

 

 

The answer is: E

 

17-Subepithelial separation can be seen microscopically in:

  1. Pemphigus vulgaris
  2. Mucous membrane pemphigoid
  3. Aphthous stomatitis
  4. Secondary herpes simplex
  5. None of the above

 

 

 

 

 

The answer is: B

 

18-In which of the following oral sites does mucous membrane pemphigoid usually present:

  1. Gingiva
  2. Lip
  3. Floor of the mouth
  4. Hard palate
  5. Tongue

 

 

 

 

 

The answer is: A

 

19-Severe recurrent herpes simplex labialis is best treated with:

  1. Zovirax ointment
  2. Topically applied ethanol
  3. Topical corticosteroid
  4. Systemic corticosteroid
  5. Acyclovir tablets

 

 

 

 

 

The answer is: E

 

20-Which of following conditions best describes a 16-year-old patient with three large painful tongue ulcers that measure greater than 0.5 cm in diameter each. He also has scars in his buccal mucosa from previous lesions. The ulcers generally last several weeks before healing.

  1. Syphilis
  2. Squamous cell carcinoma
  3. Minor aphthous stomatitis
  4. Major aphthous stomatitis
  5. Tuberculosis

 

 

 

 

 

 

The answer is: D

 

21-Which of the following shows features of acantholytic bullae:

  1. Cicatricial pemphigoid
  2. Pemphigus vulgaris
  3. Squamous cell carcinoma
  4. Herpetiform aphthae
  5. None of the above

 

 

 

 

 

The answer is: B

 

22-All of the following can present with bilateral buccal mucous white lesion EXCEPT:

  1. Cannon's disease (white sponge nevus)
  2. Witkop's disease (HBID)
  3. Secondary herpes zoster
  4. Leukoedema
  5. Cheek chewing

 

 

 

 

 

 

The answer is: C

 

23-A patient seeks help for recurrent palatal pain. She presents with multiple punctate ulcers in the hard palate that were preceded by tiny blisters. Her lesions typically heal in about 2 weeks and reappear during stressful times. She has:

  1. Aphthous ulcers
  2. Recurrent primary herpes
  3. Recurrent secondary herpes
  4. Erythema multiforme
  5. Discoid lupus

 

 

 

 

 

The answer is: C

 

24-An asymptomatic single deep indurated craterform lesion on the posterior lateral border of the tongue of a 50 years old patient can be all of the following EXCEPT:

  1. Squamous cell carcinoma
  2. Chronic traumatic ulcer
  3. Secondary herpes
  4. Syphilis
  5. Histoplasmosis

 

 

 

 

 

The answer is: C

 

25-All of the following conditions are contagious EXCEPT:

  1. Oral histoplasmosis
  2. Pemphigus vulgaris
  3. Cold sores
  4. Primary herpes
  5. Oral chancre

 

 

 

 

 

The answer is: B

 

26-Which of the following conditions contains Intercellular deposits of IgG in its epithelium:

  1. Cicatricial pemphigoid
  2. Lichen planus
  3. Pemphigus vulgaris
  4. Aphthous ulcers
  5. Stevens Johnson syndrome

 

 

 

 

 

 

The answer is: C

 

27- A child of 14 months presents with blood-crusted lips, pyrexia and widespread oral ulceration. What is the most likely diagnosis:

  1. Teething
  2. Traumatic injury
  3. Primary herpetic gingivostomatitis
  4. Hand, foot and mouth
  5. Human papilloma virus

 

 

 

 

 

 

The answer is: D

 

28- Which one of the following does not causethe reactivation of herpes simplex infections:

  1. Stress
  2. Sunlight
  3. Immunosuppression
  4. Local trauma
  5. Dental caries

 

 

 

 

 

 

The answer is: E

 

29-Which of the following conditions can be considered a self-limited endemic systemic disease, caused by a Coxsackie virus, and results in an oral vesicular/ulcerative eruption of the faucial pillar and pharyngeal areas

  1. Herpangina
  2. Hand, foot, and mouth disease
  3. Shingles
  4. Varicella
  5. Lupus erythematosus

 

 

 

 

 

The answer is: A

 

30- A 12 year old child who has had chicken pox previously presents with vesicles in and around his left ear, hearing loss and some facial nerve weakness. what is the diagnosis:

  1. Herpes simplex 1 reactivation
  2. Herpes simplex 2 reactivation
  3. Ramsay-Hunt Syndrome
  4. Coxsackie viral infection
  5. Infectious mononucleosis

 

 

 

 

 

The answer is: C 

 

31-The irradiations to the head region do no cause:

  1. Xerostomia
  2. Osteoradionecrosis
  3. Radiation caries
  4. Interference with tooth development
  5. Ramsay Hunt syndrome

 

 

 

 

 

The answer is: E

 

32-Koplik’s spots are an early intraoral manifestation of:

  1. Varicella
  2. Variola
  3. Rubella
  4. AIDS
  5. Mumps

 

 

 

 

 

The answer is: C

 

33-Which of the following conditions is NOT treated with corticosteroids:

  1. Pemphigus
  2. Pemphigoid
  3. Erythema multiforme
  4. Primary herpes gingivostomatitis
  5. Herpetiform aphthous ulcers

 

 

 

 

 

 

The answer is: D

 

34-A positive Nikolsky sign can be seen in:

  1. Histoplasmosis
  2. Major aphthae
  3. Minor aphthae
  4. Mucous membrane pemphigoid
  5. None of the above

           

 

 

 

 

The answer is: D

 

35-Circulating antibodies to herpes simplex virus cannot be seen in which of the following:

  1. Patient with active herpes labialis
  2. Patient with active intraoral herpes
  3. Patient with past history herpes whitlow
  4. Patient with past history of mild primary herpes
  5. None of the above

 

 

 

 

 

The answer is: E

 

36-Herpes simplex labialis is treated with:

  1. Topical acyclovir
  2. Systemic acyclovir
  3. Systemic prednisone
  4. Penicillin
  5. Valium

 

 

 

 

 

The answer is: B

 

37- Coxsackie virus is the cause of which of the following conditions:

  1. Zoster
  2. Whitlow
  3. Hand, foot, and mouth disease
  4. Measles
  5. Aphthous ulcers

 

 

 

 

 

The answer is: C

 

38-Secondary varicella-zoster virus infections are:

  1. Symmetrical in distribution
  2. More prevalent in immunocompromised patients
  3. Result from virus reinfection
  4. Are usually asymptomatic
  5. None of the above

 

 

 

 

 

The answer is: B

 

 

39-Multiple self-limited ulcers are seen in the pharynx of patients with which of the following conditions:

  1. Herpangina
  2. Hand, foot, and mouth disease
  3. Measles
  4. Secondary herpes simplex infections
  5. Primary syphilis

 

 

 

 

 

The answer is: A

 

40- Only one of the following vesiculo-bullous disorders is classified as a nonhereditary condition and most commonly presented on the skin:

  1. Pemphigus vulgaris
  2. Cicatricial pemphigoid
  3. Epidermolysis bullosa
  4. Lupus erythematosus
  5. Bullous pemphigoid

 

 

 

 

 

 

The answer is: E