MCQs in Oral Pathology

Chapter 2: Ulcerative Conditions

 

 

1-All the following conditions are painless EXCEPT:

  1. Idiopathic leukoplakia
  2. Minor aphthous ulcer
  3. Idiopathic erythroplakia
  4. Lingual varix
  5. None of the above

 

 

 

 

 

The answer is: B

 

2-Squamous cell carcinoma of the right floor of the mouth would most likely metastasize to which of the following sites

  1. Submental lymph nodes
  2. Submandibular lymph nodes, right side
  3. Submandibular lymph nodes left side
  4. Lung
  5. Mandible

 

 

 

 

The answer is: B

 

3-Which of the following is true about oral primary syphilis:

  1. Is occasionally preceded by lung disease
  2. Is treated with long-term high-dose amphotericin B
  3. Is not a contagious lesion
  4. May be confused clinically with secondary herpes
  5. None of the above

 

 

 

 

The answer is: E

4-Which of the following conditions is mediated by IgE:

  1. Contact allergy
  2. Angioedema
  3. Erythema multiforme
  4. Aphthous ulcers
  5. None of the above

 

 

 

 

 

The answer is: B

 

5-The most common site of oral squamous cell carcinoma out of the following answers is:

  1. Hard palate
  2. Soft palate
  3. Gingiva
  4. Buccal mucosa
  5. The floor of the mouth

 

 

 

 

 

The answer is: E

 

6-A 30 years old male patient presents with a chronic tongue ulcer of at least 4 weeks duration. This could be all the following EXCEPT:

  1. Chancre
  2. Minor aphthous ulcer
  3. Major aphthous ulcer
  4. Tuberculosis
  5. Squamous cell carcinoma

 

 

 

 

 

The answer is: B

 

7-All the following are true about tuberculosis EXCEPT:

  1. Increasing incidence in the United States
  2. Oral lesions typically follow mucosal implantation from a lung infection
  3. Treatment is with long-term high-dose penicillin
  4. Causes a granulomatous tissue reaction
  5. Presents orally as a chronic ulcer(s)

 

 

 

 

The answer is: C

 

8-Which of the following is true regarding infections by Mucor and Rhizopus:

  1. Endemic in the Midwest
  2. Are caused by inhalation of gram-negative bacteria
  3. Are treated with long-term high-dose penicillin
  4. May be confused with secondary herpes
  5. None of the above

 

 

 

 

 

The answer is: E

 

9-Actinomycosis is treated with

  1. Penicillin
  2. Nystatin
  3. Amphotericin B
  4. Isoniazid
  5. Ganciclovir

 

 

 

 

 

The answer is: A

 

10-A young adult male patient presents to your clinic complaining of  flat ulcers in his palate, tongue, and buccal mucosa. The lesions measured approximately 1 cm in diameter and were preceded briefly by bullae. The lesions have been persistent for 6 weeks. This lesion is only limited to his oral cavity. Microscopically, you can see acantholysis with intraepithelial separation. This condition is most likely to be :

  1. Erythema multiforme
  2. Discoid lupus erythematosus
  3. Primary herpes simplex infection
  4. Mucous membrane pemphigoid
  5. None of the above

 

 

 

 

 

The answer is: E

 

11-Which of the following is true about oral aphthous ulcers:

  1. Occur because of reinfection by HSV
  2. Can be diagnosed by cytologic smears
  3. Are typically preceded by vesicles
  4. May be seen occasionally on the vermilion of the lips
  5. None of the above

 

 

 

 

 

The answer is: E

 

12-Which of the following conditions results in scarring following healing:

  1. Herpes simplex labialis
  2. Erythema multiforme
  3. Minor aphthae
  4. Major aphthae
  5. None of the above

 

 

 

 

The answer is: D

 

13-Which of the following microscopic features is the single most important feature for the diagnosis of oral squamous cell carcinoma:

  1. Invasion
  2. A lymphocytic infiltrate
  3. Pleomorphism
  4. Encapsulation
  5. Hyperchromatism

 

 

 

 

 

The answer is: A

 

14-Squamous cell carcinoma presents as all of the following EXCEPT:

  1. Increased mitotic rate
  2. Dyskeratosis
  3. Nuclear pleomorphism
  4. Acanthosis
  5. Nuclear hyperchromatism

 

 

 

 

 

The answer is: D

 

15-A 2 cm indurated red mass in the floor of the mouth with an asymptomatic and indurated submandibular lymph nodes on the same side of a heavy smoker's mouth is most likely to be:

  1. Lichen planus
  2. Erythroplakia
  3. Carcinoma in situ
  4. Squamous cell carcinoma
  5. None of the above

 

 

 

 

 

The answer is: D

 

16-All of the following presents on the gingiva, EXCEPT:

  1. Primary herpes infection
  2. Secondary herpes
  3. Recurrent minor aphthae
  4. Pyogenic granuloma
  5. Peripheral giant cell granuloma

 

 

 

 

 

The answer is: C

 

17-Which of the following factors determine the prognosis of oral squamous cell carcinoma:

  1. Symptomology
  2. Microscopic subtype
  3. Clinical stage
  4. Inflammatory cell infiltrate
  5. All the above

 

 

 

 

 

The answer is: C

 

18-Oral  squamous cell carcinomas presents clinically as:

  1. Indurated nonhealing ulcer
  2. White patch
  3. Red patch
  4. Irregular mass
  5. All the above

 

 

 

 

 

The answer is: E

 

 19- Which of following conditions should be treated with Penicillin:

  1. Tuberculosis
  2. Histoplasmosis
  3. Aphthous ulcers
  4. Actinomycosis
  5. Intraoral herpes

 

 

 

 

 

 

The answer is: D

 

20- Which of the following conditions is considered a iatrogenic injury:

  1. Traumatic granuloma
  2. Factitial ulcer
  3. Cotton roll-induced ulcer
  4. Frictional hyperkeratosis
  5. All the above

 

 

 

 

 

The answer is: C

 

21- Target lesions are associated with which one of the following conditions:

  1. Stevens-Johnson syndrome
  2. Major aphthous stomatitis
  3. Pemphigus
  4. Pemphigoid
  5. Syphilis

 

 

 

 

 

The answer is: A

 

22- A 31-year-old male patient to your clinic with a chronic draining sinus at the inferior margin of his jaw. He also has low grade mandibular bone pain several weeks after the extraction of a molar in the area. This history is typical of which of the following:

  1. Post zoster neuralgia
  2. Drug reaction
  3. Actinomycosis
  4. Lupus erythematosus
  5. Gumma

 

 

 

 

 

The answer is: C

 

23- Granulomatous inflammation is feature of which of the following conditions:

  1. Aphthous ulcers
  2. Histoplasmosis
  3. Pemphigus Vulgaris
  4. Erythema multiforme
  5. Angioedema

 

 

 

 

 

The answer is: B

 

24- The pathological physiology for angioedema is related to which of the following:

  1. Drug overdose
  2. Antigen interaction with IgE-coated mast cells
  3. Lymphocyte immune reaction
  4. Drug side effect
  5. Circulating IgG combining with circulating antigen

 

 

 

 

 

The answer is: B

 

25-Which of the following inflammatory cells characterizes the infiltrate seen microscopically in tuberculosis, histoplasmosis, and other deep fungal infections:

  1. Plasma cells
  2. Macrophages
  3. Neutrophils
  4. Basophils
  5. Eosinophils

 

 

 

 

 

The answer is: B

 

26-Aphthous ulcers can be treated using:

  1. Chemical cautery
  2. Excision
  3. Topical penicillin
  4. Mycelex troches (clotrimazole)
  5. Corticosteroids

 

 

 

 

The answer is: E

 

27-Lupus erythematosus is caused by which of the following:

  1. Coxsackie virus
  2. Herpes simplex virus
  3. Immunodeficiency
  4. Vitamin A deficiency
  5. Autoimmunity

 

 

 

 

 

The answer is: E

 

28-Drug hypersensitivity and herpes simplex infections have been implicated in the etiology of which of the following:

  1. Major aphthous ulcers
  2. Epidermolysis bullosa
  3. Erythema multiforme
  4. White sponge nevus
  5. Mucous membrane pemphigoid

 

 

 

 

 

 

The answer is: C

 

29-Which of the following is the highest risk factor for oral squamous cell carcinomas:

  1. Ethanol
  2. Viruses
  3. Trauma
  4. Tobacco
  5. Poor oral hygiene Data

 

 

 

 

 

The answer is: D

 

30-Phycomycosis is a term that refers to a group of infections also known as:

  1. Superficial fungal infections
  2. Deep fungal infections
  3. Opportunistic fungal infections
  4. Fungus-like bacterial infections
  5. None of the above

 

 

 

 

 

 

The answer is: B

 

31-which of the following locations are aphthous ulcers not seen in healthy patients:

  1. The vestibule of the lower lip
  2. Tongue
  3. Buccal mucosa
  4. Faucial pillars
  5. Hard palate

 

 

 

 

 

The answer is: E

 

32-Individuals with arrested tuberculosis:

  1. Do not react to TB antigen skin challenge
  2. Have a chronic cough
  3. May not have been aware of a primary infection
  4. Are permanently cured of their disease
  5. None of the above

 

 

 

 

 

The answer is: C

 

33-Diffuse soft swelling of the lips and neck following the ingestion of drugs, shellfish, or nuts is known as:

  1. Fixed drug reaction
  2. Anaphylaxis
  3. Urticaria
  4. Acquired angioedema
  5. Contact allergy

 

 

 

 

 

The answer is: D

 

34-Which of the following cases is most likely not to develop oral squamous cell carcinoma:

  1. A patient who is a long-term alcoholic and smoker
  2. Patient with Plummer-Vinson syndrome
  3. Previously treated oral cancer patient
  4. Patient with a 30-year history of snuff dipping
  5. Patient with a 30-year history of denture wearing

 

 

 

 

 

The answer is: E

 

35-The chances that a patient treated for squamous cell carcinoma of the floor of the mouth metastatic to the ipsilateral neck lymph nodes to survive for 5 years would be approximately:

  1. 0%
  2. 25%
  3. 50%
  4. 75%
  5. 95%

 

 

 

 

 

The answer is: B

 

36-Which of the following statements is true about oral tuberculosis:

  1. Is granulomatous in microscopic appearance
  2. May appear clinically like primary syphilis
  3. Is usually secondary to lung infection
  4. Is contagious
  5. All the above

 

 

 

 

 

 

The answer is: E

 

37-The first site that oral squamous cell carcinoma of the posterior lateral border of the tongue will Metastasis to is:

  1. Submental lymph nodes
  2. Submandibular lymph nodes
  3. Mandibular bone
  4. Supraclavicular lymph nodes
  5. Lung

 

 

 

 

 

The answer is: B

 

38-A medically fit young adult male patient presents to your clinic complaining of multiple oral ulcers, several penile ulcers, and ocular pain. The lesions were not preceded by blisters. These features are most likely to be in:

  1. Secondary syphilis
  2. Erythema multiforme
  3. Hereditary benign intraepithelial dyskeratosis
  4. Primary herpes simplex infection
  5. Behcet's syndrome

 

 

 

 

 

The answer is: E

 

39-which of following sites does oral squamous cell carcinoma presents more commonly:

  1. Gingiva
  2. Palate
  3. The floor of the mouth
  4. Lateral tongue
  5. Buccal mucosa

 

 

 

 

 

The answer is: D

 

40- The lesion in the figure above is ulcerated with a firm raised edge; it is likely to be:

  1. Erythema migrans
  2. Median rhomboid glossitis
  3. Basal cell carcinoma
  4. Squamous cell carcinoma
  5. Traumatic ulcer

 

 

 

 

 

The answer is: D

 

41- What is the male to female ratio of the prevalence of recurrent aphthous stomatitis:

  1. 3:1
  2. 2:1
  3. 1:1
  4. 1:2
  5. 1:3

 

 

 

 

 

The answer is: C

 

42- Regarding aphthous ulcers:

  1. They are more common in males.
  2. The herpetiform-type are more common in males.
  3. Haematinic deficiencies are detected in approximately 50% of cases.
  4. They can be associated with cessation of smoking.
  5. They are often helped by the used of antidepressants.

 

 

 

 

 

The answer is: D

 

43- Carcinoma of the lip:

  1. Is commoner in the upper lip.
  2. Is often caused by chewing betel nut/paan.
  3. Has a worse prognosis than intra-oral carcinoma.
  4. Is principally caused by alcohol consumption.
  5. None of the above.

 

 

 

 

 

The answer is: E

 

45-Immunocompromised patients are at risk for the development of which of the following:

  1. Tuberculosis
  2. Histoplasmosis
  3. Herpes simplex virus infections
  4. Oral warts
  5. All the above

 

 

 

 

 

The answer is: E

 

46- Which of the following statements regarding oral squamous cell carcinoma in the UK are correct?

  1. The incidence of lip cancer is as about the same as the incidence of tongue cancer
  2. The 5-year survival rate for patients with lip cancer is the better than the 5-year survival rate for those with tongue cancer in females but not in males
  3. The incidence of oral cancer in females is greater than that in males
  4. The 2-year survival rates for patients with stage I and stage II oral cancer are the same
  5. Overall females have a slightly better survival rate for oral cancer than males

 

 

 

 

 

 

The answer is: E

 

 47- The appropriate management of the lesion shown in Q 5.27 may involve:

  1. Incisional biopsy.
  2. Fine needle aspirate.
  3. Smear for 
  4. Excisional biopsy.
  5. Full blood count to rule out haematinic deficiencies as the cause of the oral lesion.

 

 

 

 

 

The answer is: A

 

48- Atrophy of the pharyngeal, and gastric mucosa, koilonychia (spoon nails), and predisposition to oral carcinoma in postmenopausal women are features of:

  1. Iron deficiency anemia
  2. Pernicious anemia
  3. Sturge-Weber-Dimitri syndrome
  4. Plummer-Vinson syndrome
  5. Trisomy 21

 

 

 

 

The answer is: D

 

49- The so-called “split papule,” an erosive lesion involving the commissure of the lips, is actually:

  1. An aphthous ulcer
  2. A traumatic ulcer
  3. A mucous patch
  4. A fever blister
  5. Koplik’s spot

 

 

 

 

 

The answer is: C

 

50-Gummas are chronic inflammatory lesions associated with which of the following:

  1. Gonorrhea
  2. Tertiary syphilis
  3. Erythema multiforme
  4. Behcet's syndrome
  5. None of the above

 

 

 

 

The answer is: B

 

51- The stigmata of congenital syphilis does not include:

  1. Saber shins
  2. Interstitial keratitis
  3. Eighth nerve deafness
  4. Rhagades
  5. Cleft lip

 

 

 

 

 

The answer is: E

 

52-The “Ghon complex “is associated with:

  1. Primary of childhood tuberculosis
  2. The adrenogenital syndrome
  3. Uveoparotid fever or Heerfordt’s syndrome
  4. Histiocytosis
  5. AIDS

 

 

 

 

 

The answer is: A

 

53-Increased Monocytic count is seen in Typhus and which of the following conditions:

 

  1. SABE
  2. Herpes LAbialis
  3. HIV
  4. Characteristic Parasitic Infections

 

 

 

 

 

 

The answer is: A

 

54-Which of the following conditions is painless:

  1. Squamous cell carcinoma
  2. Secondary herpes
  3. Zoster
  4. Minor aphthae
  5. Acute traumatic mucosal ulcer

 

 

 

 

The answer is: A

 

55-Oral aphthous ulcers are due to:

  1. Nutritional deficiency
  2. Cell-mediated immune defect
  3. Viral infection
  4. Hormonal imbalance
  5. Stress

 

 

 

 

 

The answer is: B

 

56-Aphthous ulcer type lesions may be seen in which of the following systemic conditions:

  1. Diabetes mellitus
  2. Crohn's disease
  3. Hypertension
  4. Thrombocytopenia
  5. None of the above

 

 

 

 

 

The answer is: B

 

57-Herpetiform aphthous ulcers occurs due to:

  1. Herpes simplex virus
  2. Varicella-zoster virus
  3. Epstein-Barr virus
  4. Streptococci
  5. None of the above

 

 

 

 

 

 

The answer is: E

 

58-Which of the following can be the cause of oral squamous cell carcinoma:

  1. Human papillomavirus
  2. Chronic trauma
  3. Vitamin deficiency
  4. Alcohol
  5. Tobacco

 

 

 

 

 

The answer is: E

 

59-Granulomatous inflammation is seen in which of the following cells:

  1. Mast cells
  2. Neutrophils
  3. Plasma cells
  4. Lymphocytes
  5. None of the above

 

 

 

 

 

The answer is: E

 

60-Granulomatous inflammation is seen in which of the following conditions:

  1. Tuberculosis
  2. Histoplasmosis
  3. Blastomycosis
  4. Coccidioidomycosis
  5. All the above

 

 

 

 

 

The answer is: E

 

61-Target skin lesions are the classic cutaneous counterpart of which of the following oral ulcerative diseases:

  1. Chronic lupus erythematosus
  2. Acute lupus erythematosus
  3. Behcet's syndrome
  4. Secondary syphilis
  5. Erythema multiforme

 

 

 

 

 

The answer is: E

 

62-Bone pain, abnormal serum immunoglobulins, and punched out skull lesions in a 65-year-old man would suggest which of the following:

  1. Metastatic carcinoma of the breast
  2. Hyperparathyroidism
  3. Langerhans cell disease (idiopathic histiocytosis)
  4. Plasma cell myeloma
  5. Osteosarcoma

 

 

 

 

 

The answer is: D