MCQs in Oral Pathology

Chapter 15: Metabolic and genetic diseases

 

 

1-Which of the following is true about Paget's disease:

  1. Typically occurs in teenagers
  2. Is caused by excessive production of growth hormone
  3. Results in premature loss of teeth
  4. Predisposes the patient to fracture and infection
  5. All the above

                      

 

 

 

 

 

The answer is: D

 

2-A normal clot retraction time, which is independent of coagulation time, is indicative of a normal number of circulating:

  1. Platelets
  2. Lymphocytes
  3. Monocytes
  4. Red blood cells
  5. Neutrophils

 

 

 

 

 

 

The answer is: A

 

3-Which of the following conditions can become malignant:

  1. Desmoplastic fibroma
  2. Odontogenic myxoma
  3. Paget's disease
  4. Cementoblastoma
  5. All the above

 

 

 

 

 

 

The answer is: C

 

4-Abnormally increased serum calcium and giant cell lesions of bone are seen in:

  1. Langerhans cell disease
  2. Hyperparathyroidism
  3. Osteosarcoma of the jaw
  4. Osteopetrosis
  5. None of the above

 

 

 

 

 

 

The answer is: B

 

5-which of the following conditions can occur due to drugs ingestion:

  1. Herpetiform aphthous ulcers
  2. Geographic tongue
  3. Cicatricial pemphigoid
  4. Mucous patches
  5. None of the above

 

 

 

 

 

 

The answer is: E

 

6-Multiple osteolytic lesions of jaws, kidney stones, and peptic ulcer are features of:

  1. Cherubism
  2. Basal cell nevus syndrome
  3. McCune-Albright syndrome
  4. Hyperparathyroidism
  5. None of the above

 

 

 

 

 

 

The answer is: D

 

7-A generic term for opportunistic mycotic infections that affect the upper air passages in uncontrolled diabetics is known as:

  1. Actinomycosis
  2. Phycomycosis
  3. Histoplasmosis
  4. Gumma
  5. Coccidioidomycosis

 

 

 

 

 

 

The answer is: B

 

8-Hypersensitivity reactions to ingested immunogenic drugs appear on skin and mucosa as:

  1. Erythema
  2. Ulceration
  3. Lichenoid reactions
  4. Vesiculation
  5. All the above

 

 

 

 

 

 

The answer is: E

 

9-While examining a child at your clinic, you take a panoramic xray and notice a bilateral multilocular radiolucent lesions. Microscopically, the lesions were composed of fibroblasts and numerous multinucleated giant cells. This condition is most likely to be:

  1. Paget's disease
  2. Ectodermal dysplasia
  3. Osteopetrosis
  4. Cherubism
  5. Fibrous dysplasia

 

 

 

 

 

 

The answer is: D

 

10-An opportunistic mycotic infection that affects the upper air passages in uncontrolled diabetics is known as:

  1. Actinomycosis
  2. Mycoplasma
  3. Mucormycosis
  4. Tuberculosis
  5. Primary syphilis

 

 

 

 

 

 

The answer is: C

 

11-An immunocompromised patient is at risk for development of which of the following:

  1. Primary herpes
  2. Secondary herpes
  3. Tuberculosis
  4. Candidiasis
  5. All the above

 

 

 

 

 

The answer is: E

 

12-The most likely diagnosis in a 23-year-old, mentally alert, male dwarf with disproportionate arm and leg to body growth, prominent forehead, and retruded maxilla is:

  1. Cretinism
  2. Pituitary dwarfism
  3. Acromegaly
  4. Achondroplasia
  5. Eagle’s syndrome

 

 

 

 

 

 

  The answer is: D

 

13- The blood of a patient with an acute infectious process would be expected to demonstrate:

  1. Lymphocytosis
  2. Leukocytosis
  3. Monocytosis
  4. Leukopenia
  5. Erythrocytosis

 

 

 

 

 

 

The answer is: B

 

14- Histiocystosis X, sometimes referred to as non-lipid reticuloendotheliosis, includes:

  1. Letterer-Siwe disease
  2. Hand-Schuler-Christian disease
  3. Eosinophilic Granuloma
  4. Histiocytoma
  5. All of above

 

 

 

 

 

 

 The answer is: E

 

15- Features of multiple bone radiolucencies, hypercalcemia, hypophosphatemia, and loss of lamina dura and indicative of:

  1. Acromegaly
  2. Hyperparathyroidism
  3. Hypothyroidism
  4. Multiple myeloma
  5. Osteitis deformans

 

 

 

 

 

 

The answer is: B

 

16- A patient with oral moniliasis that does not respond to nystatin therapy should be evaluated for the following except:

  1. Diabetes inspidus
  2. Diabetes mellitus
  3. Hyperparathyroidism
  4. Malignant lymphoma
  5. Raised Ca+ in serum

 

 

 

 

 

 

The answer is: A

 

17- The classic triad of Hand-Schuler-Christian disease includes lesions of bone, exopthalmos and:

  1. Diabetes insipidus
  2. Hepatosplenomegaly
  3. Diabetes mellitus
  4. Albuminuria
  5. Hypothyroidism

 

 

 

 

 

 

The answer is: A

 

18-The Melkersson-Rosenthal syndrome is characterized by facial paralysis, Cheilitis granulomatosa, and:

  1. Black Hairy tongue
  2. Scrotal tongue
  3. Geographic tongue
  4. Bifid tongue
  5. White Hairy tongue

 

 

 

 

 

 

 The answer is: B

 

19- A 8 year old child has increased horizontal anterior bone loss with premature loss of deciduous teeth. There is defective cementum and shows excretion of phosphoethanolamine in the urine. The child is suffering from:

 

  1. Hypophosphophatasia
  2. Vit. D resistant rickets
  3. Juvenile Periodontitis
  4. Osteomalacia

 

 

 

 

 

 

The answer is: A

 

20- A 9 year old female patient with severe oral ulceration is suffering with salivation, fever, headache and malaise. The peeling of skin of hand and sole in noted. There is increased tendency for sweating. She is also giving one month history of using a new teething gel available in the market, the most probable prognosis is:

 

  1. Erosive lichen Planus
  2. Epidermolysis Bullosa
  3. Acrodynia
  4. Steven Johnsons syndrome

 

 

 

 

 

 

The answer is: C

 

21- Ehler Danlos Syndrome is :

 

  1. Autosomal Dominant
  2. Autosomal Recessive
  3. X-linked dominant
  4. X-linked recessive

 

 

 

 

 

 

The answer is: A

 

22-Infections and jaw fracture would most likely complicate which of the following:

  1. Adenomatoid odontogenic tumor
  2. Osteopetrosis
  3. Lateral root cyst
  4. Compound odontoma
  5. Fibrous dysplasia

 

 

 

 

 

 

The answer is: B

 

23-Hyperthyroidism can lead to:

  1. Radiographic evidence of loss of lamina dura
  2. Increased serum calcium
  3. Multiple radiolucencies
  4. Giant cell lesions of the jaws
  5. None of the above

 

 

 

 

 

 

The answer is: E

 

24-Early exfoliation of teeth would most happen with which of the following conditions:

  1. Odontoma
  2. Hypophosphatasia
  3. Odontogenic keratocyst
  4. Eruption cyst
  5. Cleidocranial dysplasia

 

 

 

 

 

 

The answer is: B

 

25-Which of the following is defined as a vascular fibroblastic matrix in which there are numerous multinucleated giant cells:

  1. Hypophosphatasia
  2. Hypothyroidism
  3. Hyperthyroidism
  4. Hyperparathyroidism
  5. All the above

 

 

 

 

 

 

The answer is: D

 

26-Impacted and supernumerary teeth are features of:

  1. McCune-Albright syndrome
  2. Cleidocranial dysplasia
  3. Gardner's syndrome
  4. Ectodermal dysplasia
  5. Regional odontodysplasia

 

 

 

 

 

 

The answer is: B

 

27-Uniform and symmetric bilateral hand and jaw enlargement are features of:

  1. Fibrous dysplasia
  2. Acromegaly
  3. Garry's osteomyelitis
  4. Ossifying fibroma
  5. None of the above

 

 

 

 

 

 

The answer is: B

 

28-The rare genetic disorder that results in generalized bony sclerosis is known as:

  1. Cherubism
  2. Plasma cell myeloma
  3. von Recklinghausen's disease
  4. Fibrous dysplasia
  5. Albers-Schonberg disease

 

 

 

 

 

The answer is: E

 

29-Aplasia of secondary skin structures, partial anodontia, and xerostomia are seen in:

  1. Cleidocranial dysplasia
  2. Ectodermal dysplasia
  3. Amelogenesis imperfecta
  4. Nevoid basal cell carcinoma syndrome
  5. Osteogenesis imperfecta

 

 

 

 

 

The answer is: B

 

30-A facial developmental cleft occurring to the right of the philtrum of soft tissue of the lip that extends through the alveolar bone to the nasopalatine canal, is defined as:

  1. Incomplete cleft of the palate
  2. Incomplete cleft of the lip
  3. Complete cleft of the palate
  4. Complete cleft of the lip
  5. Combined cleft of the lip and palate

 

 

 

 

 

 

The answer is: D

 

31-Hyperparathyroidism causes which of the following changes in serum chemistry:

  1. Decreased calcium
  2. Increased calcium
  3. Increased phosphorous
  4. Decreased alkaline phosphatase
  5. None of the above

 

 

 

 

 

 

The answer is: B

 

32-Determination of serum alkaline phosphatase would be significantly elevated in which of the following:

  1. Ameloblastoma
  2. Cherubism
  3. Paget's disease
  4. Ossifying fibroma
  5. Central giant cell granuloma

 

 

 

 

 

 

The answer is: C

 

33-Bilateral symmetric enlargement of the mandible or maxilla would most likely be seen in which of the following:

  1. Garre's osteomyelitis
  2. Paget's disease
  3. Osteosarcoma
  4. Fibrous dysplasia
  5. Ameloblastic fibroma

 

 

 

 

 

 

The answer is: B

 

34-Hypoplastic clavicles, delayed eruption, supernumerary teeth, and frontal bone bossing are features of:

  1. Hemifacial hypertrophy
  2. Cleidocranial dysplasia (dysostosis)
  3. Gardner's syndrome
  4. Down syndrome
  5. Multiple endocrine neoplasia syndrome (MEN III)

 

 

 

 

 

 

The answer is: B

 

35-Which of the following conditions significantly increases a patient's risk for the development of adenocarcinoma of the colon:

  1. Albright's syndrome
  2. Neurofibromatosis
  3. Cleidocranial dysplasia
  4. Gardner's syndrome
  5. None of the above

 

 

 

 

 

 

The answer is: D

 

36-All of the following may be seen in patients with hyperparathyroidism EXCEPT:

  1. Multiple lucent jaw lesions
  2. Elevated serum acid phosphatase
  3. Loss of lamina dura
  4. Elevated serum calcium
  5. Parathyroid adenoma

 

 

 

 

 

 

The answer is: B

 

37-Congenital anodontia (partial or complete) is a feature of which of the following:

  1. Hereditary ectodermal dysplasia
  2. Dentin dysplasia
  3. Gardner's syndrome
  4. Cleidocranial dysplasia (dysostosis)
  5. None of the above

 

 

 

 

 

 

The answer is: A